A novel nongenetic murine model of hyperglycemia and hyperlipidemia-associated aggravated atherosclerosis
S. Gaul, K. Shahzad, R. Medert, I. Gadi, C. Meader, D. Schumacher, A. Wirth, S. Ambreen, S. Fatima, J.-N. Boeckel, H. Khawaja, J. Haas, M. Brune, P. P. Nawroth, B. Isermann, , M. Freichel
This paper establishes a nongenetic mouse model to study atherosclerosis under hyperlipidemia and hyperglycemia conditions and evaluates diet effects on plaque severity.
bioRxiv · Nov 11, 2021 · PreprintPharmacology & Toxicology