Author

R. Medert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

M. Freichel· 3 shared T. Fleming· 2 shared A. Cornean· 1 shared A. Wirth· 1 shared B. Isermann· 1 shared C. Meader· 1 shared C. Rodemer· 1 shared D. Schumacher· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

M. Freichel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Streamlined generation of CRISPR/Cas9-mediated single-cell knockout clones in murine cell lines.

T. Hub, A. Cornean, K. Round, T. Fleming, M. Freichel, R. Medert

This paper describes a method to efficiently generate and identify CRISPR/Cas9-mediated single-cell knockout clones in murine cell lines within 3-4 weeks.

bioRxiv · Oct 20, 2023 · PreprintCell Biology

Induction of mitochondrial heat shock proteins and mitochondrial biogenesis in endothelial cells upon acute methylglyoxal stress: Evidence for hormetic autofeedback

R. Bulkescher, T. Fleming, C. Rodemer, R. Medert, M. Freichel, M. P. Mayer, J. Szendroedi, S. Herzig, J. Zemva

This study shows that knocking out HSPA1A/HSPA1B in mouse endothelial cells leads to increased mitochondrial biogenesis and chaperone expression under methylglyoxal stress.

bioRxiv · Nov 30, 2021 · PreprintCell Biology

A novel nongenetic murine model of hyperglycemia and hyperlipidemia-associated aggravated atherosclerosis

S. Gaul, K. Shahzad, R. Medert, I. Gadi, C. Meader, D. Schumacher, A. Wirth, S. Ambreen, S. Fatima, J.-N. Boeckel, H. Khawaja, J. Haas, M. Brune, P. P. Nawroth, B. Isermann, , M. Freichel

This paper establishes a nongenetic mouse model to study atherosclerosis under hyperlipidemia and hyperglycemia conditions and evaluates diet effects on plaque severity.

bioRxiv · Nov 11, 2021 · PreprintPharmacology & Toxicology