TGF-β1 drives Th9 but not Treg cells upon allergen exposure
S. Musiol, F. Alessandrini, C. A. Jakwerth, A. M. Chaker, E. Schneider, F. Guerth, I. Ghiordanescu, J. T. Ullmann, J. Kau, M. Plaschke, S. Haak, T. Buch, C. B. Schmidt-Weber, U. M. Zissler
This study shows TGF-β1 promotes Th9 cells but not Tregs in allergic inflammation, suggesting TGF-β inhibition could be a therapeutic strategy for allergies and asthma.
bioRxiv · Aug 18, 2021 · PreprintImmunology