Author

F. Alessandrini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

C. B. Schmidt-Weber· 2 shared A. M. Chaker· 1 shared A.-M. Maier· 1 shared C. A. Jakwerth· 1 shared C. Barone· 1 shared C. Hoffmann· 1 shared C. Ohnmacht· 1 shared E. Schneider· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

C. B. Schmidt-Weber

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Lung epithelial CYP1 activity regulates aryl hydrocarbon receptor dependent allergic airway inflammation

F. Alessandrini, R. de Jong, M. Wimmer, A.-M. Maier, I. Fernandez, M. Hils, J. Buters, T. Biedermann, U. Zissler, C. Hoffmann, J. Esser-von-Bieren, C. B. Schmidt-Weber, C. Ohnmacht

This study investigates the role of CYP1 family members and AhR in lung epithelial regulation of allergic airway inflammation, finding that CYP1B1 deficiency exacerbates inflammation.

bioRxiv · Sep 20, 2021Immunology

TGF-β1 drives Th9 but not Treg cells upon allergen exposure

S. Musiol, F. Alessandrini, C. A. Jakwerth, A. M. Chaker, E. Schneider, F. Guerth, I. Ghiordanescu, J. T. Ullmann, J. Kau, M. Plaschke, S. Haak, T. Buch, C. B. Schmidt-Weber, U. M. Zissler

This study shows TGF-β1 promotes Th9 cells but not Tregs in allergic inflammation, suggesting TGF-β inhibition could be a therapeutic strategy for allergies and asthma.

bioRxiv · Aug 18, 2021 · PreprintImmunology

Sox2-dependent maintenance of mouse oligodendroglioma involves the Sox2-mediated downregulation of Cdkn2b, Ebf1, Zfp423 and Hey2

C. Barone, M. Buccarelli, F. Alessandrini, M. Pagin, L. Rigoldi, I. Sambruni, R. Favaro, S. Ottolenghi, R. Pallini, L. Ricci-Vitiani, P. Malatesta, S. K. Nicolis

This study identifies four genes, Cdkn2b, Ebf1, Zfp423, and Hey2, whose inhibition by Sox2 is critical for maintaining glioma cancer stem cell properties, suggesting new therapeutic targets.

bioRxiv · Mar 4, 2020Cancer Biology