BiophysicsbioRxiv
The C-terminus of alpha-Synuclein regulates its dynamic cellular internalization by Neurexin 1 beta
M. Birol, I. I. Dominguez Munoz, E. Rhoades
This study identifies the role of alpha-Synuclein's C-terminus in its internalization via Neurexin 1 beta, showing that truncation beyond residue 90 prevents internalization and that S-N1{beta} interactions may be therapeutically targeted.
DOI 10.1091/mbc.e22-11-0496