Thermodynamic Stabilization of Human Frataxin
R. Nunez-Franco, A. Torres-Mozas, C. D. Navo, A. Schedlbauer, M. Azkargorta, I. Iloro, F. Elortza, G. Ortega, O. Millet, F. Peccati, G. Jimenez-Oses
This study thermodynamically stabilizes human frataxin using computational methods, improving its stability and resistance to proteolysis without compromising function.
bioRxiv · Sep 8, 2023 · PreprintBiophysics