I. Jaspers

Profiling endogenous airway proteases and antiproteases and measuring proteolytic activation of Influenza HA using in vitro and ex vivo human airway surface liquid samples

This study profiles airway proteases and antiproteases in human samples and measures proteolytic activation of viral proteins, finding significant differences in cleavage rates between smokers and non-smokers.

Leveraging a Comprehensive Unbiased RNAseq Database Uncovers New Human Monocyte-Derived Macrophage Subtypes Within Commonly Employed In Vitro Polarization Methods

The paper uses an RNA-seq database to show that common in vitro macrophage polarization methods produce distinct, previously undescribed subtypes.

Woodsmoke particulates alter expression of antiviral host response genes in human nasal epithelial cells infected with SARS-CoV-2 in a sex-dependent manner

This study shows that exposure to red oak woodsmoke particulates reduces antiviral gene expression in female human nasal epithelial cells infected with SARS-CoV-2 more than in males.