An early cell shape transition drives evolutionary expansion of the human forebrain
S. Benito-Kwiecinski, S. L. Giandomenico, M. Sutcliffe, E. S. Riis, P. Freire-Pritchett, I. Kelava, S. Wunderlich, U. Martin, G. A. Wray, M. A. Lancaster
The paper uses cerebral organoids to show that a delayed cell shape transition in human neuroepithelial cells drives brain expansion compared to apes.
bioRxiv · Jul 4, 2020Evolutionary Biology