Revealing A-T and G-C Hoogsteen base pairs in stressed protein-bound duplex DNA
H. Shi, I. Kimsey, H.-F. Liu, U. Pham, M. Schumacher, H. Al-Hashimi
The paper identifies seventeen Hoogsteen base pairs in protein-bound DNA, seven of which are novel, and suggests their role in DNA repair and genomic stress.
bioRxiv · Jun 5, 2021Biophysics