Author

H.-F. Liu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 3 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:protein structure prediction· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

A. Bartesaghi· 3 shared Y. Zhou· 3 shared A. Howe· 1 shared A. P. Sikkema· 1 shared A.-S. Krebs· 1 shared B. P. Klemm· 1 shared H. Al-Hashimi· 1 shared H. Shi· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBiochemistry

A. Bartesaghi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular architecture and conservation of an immature human endogenous retrovirus

A.-S. Krebs, H.-F. Liu, Y. Zhou, J. S. Rey, L. Levintov, J. Shen, A. Howe, J. R. Perilla, A. Bartesaghi, P. Zhang

The paper determines the structure of immature HERV-K VLPs using cryoET STA, revealing conserved assembly mechanisms across retroviruses.

bioRxiv · Jun 7, 2023Microbiology

Accurate Detection of Proteins in Cryo-Electron Tomograms from Sparse Labels

Q. Huang, Y. Zhou, H.-F. Liu, A. Bartesaghi

This paper introduces a particle detection framework for cryo-electron tomograms that improves detection accuracy with minimal labeling and faster training.

bioRxiv · Sep 19, 2022 · PreprintBiochemistry

Revealing A-T and G-C Hoogsteen base pairs in stressed protein-bound duplex DNA

H. Shi, I. Kimsey, H.-F. Liu, U. Pham, M. Schumacher, H. Al-Hashimi

The paper identifies seventeen Hoogsteen base pairs in protein-bound DNA, seven of which are novel, and suggests their role in DNA repair and genomic stress.

bioRxiv · Jun 5, 2021Biophysics

Beam image-shift accelerated data acquisition for near-atomic resolution single-particle cryo-electron tomography

J. Bouvette, H.-F. Liu, X. Du, Y. Zhou, A. P. Sikkema, J. D. F. Rezende E Mello, B. P. Klemm, R. Huang, R. M. Schaaper, M. J. Borgnia, A. Bartesaghi

This paper introduces BISECT, a method that accelerates cryo-electron tomography data acquisition and improves resolution by using beam-image shift and advanced processing techniques.

bioRxiv · Sep 24, 2020Biochemistry