Early Dietary Exposures Epigenetically Program Mammary Cancer Susceptibility through IGF1-mediated Expansion of Mammary Stem Cells
Y. Zheng, L. Luo, I. lambertz, R. Fuchs-Young
This study shows early high-fat diets increase mammary cancer risk by epigenetically boosting IGF1, which expands mammary stem cells and promotes carcinogen-induced tumors.
bioRxiv · Nov 15, 2020 · PreprintCancer Biology