Trim39 regulates neuronal apoptosis by acting as a SUMO-targeted E3 ubiquitin-ligase for the transcription factor NFATc3
M. Basu Shrivastava, B. Mojsa, S. Mora, I. Robbins, G. Bossis, I. Lassot, S. Desagher
This study identifies Trim39 as an E3 ubiquitin-ligase for NFATc3, showing it regulates neuronal apoptosis through SUMO-dependent ubiquitination.
bioRxiv · Sep 29, 2020Cell Biology