Individualized VDJ recombination predisposes the available Ig sequence space
A. Slabodkin, M. Chernigovskaya, I. Mikocziova, R. Akbar, L. Scheffer, M. Pavlovic, H. Bashour, I. Snapkov, B. B. Mehta, C. R. Weber, J. Gutierrez-Marcos, L. M. Sollid, I. H. Haff, G. K. Sandve, P. A. Robert, V. Greiff
The paper shows that VDJ recombination rules vary between individuals, leading to individual-specific Ig sequence spaces.
bioRxiv · Apr 19, 2021Immunology