Author

A. Peres

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Assay:scRNA-seq· 2 Assay:CITE-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

G. Yaari· 6 shared A. M. Collins· 3 shared C. T. Watson· 3 shared J. T. Kos· 2 shared M. L. Smith· 2 shared M. Ohlin· 2 shared O. L. Rodriguez· 2 shared P. Polak· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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6 shared papersImmunology

G. Yaari

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6 papers

Recent·Most cited

IGHV allele similarity clustering improves genotype inference from adaptive immune receptor repertoire sequencing data

A. Peres, W. D. Lees, O. L. Rodriguez, N. Y. Lee, P. Polak, R. Hope, M. Kedmi, A. M. Collins, M. Ohlin, S. H. Kleinstein, C. Watson, G. Yaari

The paper introduces a new V allele naming scheme and genotype inference method for adaptive immune receptor sequencing, validated with genomic long read data and implemented in an R package.

bioRxiv · Dec 26, 2022 · PreprintImmunology

FLAIRR-seq: A novel method for single molecule resolution of near full-length immunoglobulin heavy chain repertoires

E. E. Ford, D. Tieri, O. L. Rodriguez, N. J. Francoeur, J. Soto, J. T. Kos, A. Peres, W. S. Gibson, C. A. Silver, G. Deikus, E. Hudson, C. R. Woolley, N. Beckmann, A. Charney, T. C. Mitchell, , M. L. Smith

FLAIRR-seq provides high-resolution, single-molecule characterization of immunoglobulin heavy chain repertoires, including constant region features, and identifies novel alleles.

bioRxiv · Sep 24, 2022 · PreprintImmunology

A BALB/c IGHV Reference Set, defined by haplotype analysis of long-read VDJ-C sequences from F1 (BALB/c / C57BL/6) mice

K. J. Jackson, J. T. Kos, W. Lees, W. S. Gibson, M. L. Smith, A. Peres, G. Yaari, M. Corcoran, C. E. Busse, M. Ohlin, C. T. Watson, A. M. Collins

The paper defines a BALB/c IGHV reference set by analyzing long-read VDJ-C sequences from F1 mice, identifying strain-specific variations and germline alleles not present in existing genome references.

bioRxiv · Feb 28, 2022Immunology

Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma

M. I. Rosenberg, E. Greenstein, M. Buchkovich, M. Mikl, A. Peres, E. Santoni-Rugiu, D. Reshef, A. J. Salovin, D. L. Gibbs, M. S. Irwin, A. Naranjo, I. Ulitsky, P. A. de Alarcon, V. Weigman, G. Yaari, , J. M. Maris

The paper investigates OMAS in neuroblastoma, finding polyclonal B- and T-cell infiltration and TLS enrichment, linking them to autoimmune and anti-tumor responses.

bioRxiv · Dec 14, 2021Cancer Biology

T Cell Receptor Beta Germline Variability is Revealed by Inference From Repertoire Data

A. Omer, A. Peres, O. L. Rodrigues, C. T. Watson, W. Lees, P. Polak, A. M. Collins, G. Yaari

The paper identifies undocumented polymorphisms in T cell receptor Beta genes using AIRR-seq data and shows how a single SNP affects TCR repertoire composition.

bioRxiv · May 17, 2021Immunology

Polymorphisms in immunoglobulin heavy chain variable genes and their upstream regions

I. Mikocziova, M. Gidoni, I. Lindeman, A. Peres, O. Snir, G. Yaari, L. M. Sollid

The paper identifies novel germline IGHV alleles and upstream sequence variability, challenging current immunoglobulin repertoire annotation methods.

bioRxiv · Jan 27, 2020Immunology