Defining the transcriptional signature of esophageal-to-skin lineage conversion
M. T. Bejar, P. Jimenez-Gomez, I. Moutsopoulos, B. Colom, S. Han, F. J. Calero-Nieto, B. Göttgens, I. Mohorianu, B. D. Simons, M. Alcolea
This study shows that esophageal epithelial cells can convert to hair follicle identity when exposed to skin stroma, with HIF1a inhibition blocking this transition.
bioRxiv · Feb 19, 2021 · PreprintCell Biology