I. Mohorianu

Novel 3D Approach to Model Non-Alcoholic Fatty Liver Disease using human Pluripotent Stem Cells

This paper develops a 3D multicellular model of NAFLD using hiPSC-derived liver cells to study disease mechanisms and interactions.

NOTCH1 drives immune-escape mechanisms in B cell malignancies

This study shows NOTCH1 mutations in B cell malignancies promote immune escape by upregulating PD-L1 and silencing HLA-class II, leading to poor clinical outcomes.

Defining the transcriptional signature of esophageal-to-skin lineage conversion

This study shows that esophageal epithelial cells can convert to hair follicle identity when exposed to skin stroma, with HIF1a inhibition blocking this transition.

Integrative Single-cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Haematopoiesis

The paper uses scRNA-Seq and scATAC-Seq to analyze human blood cells, identifying proliferative progenitors and epigenetic priming in haematopoiesis.

The necessary component of regulatory interactions: identification and characterization of putative regulatory motifs. Case study on the control of seminal fluid proteins through regulatory hubs in D. melanogaster

The paper was withdrawn due to overlap with a broader study using the same algorithm.

Mate choice and gene expression signatures associated with nutritional adaptation in the medfly (Ceratitis capitata)

The paper examines gene expression changes in medflies under nutritional selection and links them to mate choice behavior across generations.