Author

B. Göttgens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

I. Kucinski· 2 shared M. Barile· 2 shared A. C. Wilkinson· 1 shared A. Clay· 1 shared A. H. Cull· 1 shared B. Colom· 1 shared B. D. Simons· 1 shared D. Bode· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

I. Kucinski

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Author profile →

3 papers

Recent·Most cited

A time and single-cell resolved model of hematopoiesis

I. Kucinski, J. Campos, M. Barile, F. Severi, N. Bohin, P. N. Moreira, L. Allen, H. Lawson, M. L. R. Haltalli, S. J. Kinston, D. O'Carroll, K. R. Kranc, B. Göttgens

The paper builds a real-time, quantitative model of hematopoiesis using time-series single-cell RNA-Seq and persistent labeling, revealing lineage-specific self-renewal and differentiation properties.

bioRxiv · Sep 7, 2022 · PreprintCell Biology

A highly efficient reporter system for identifying and characterizing in vitro expanded hematopoietic stem cells

J. L. C. Che, D. Bode, I. Kucinski, A. H. Cull, F. Bain, M. Barile, G. Boyd, M. Belmonte, M. Jassinskaja, J. Rubio-Lara, M. S. Shepherd, A. Clay, A. C. Wilkinson, H. Nakauchi, S. Yamazaki, , D. G. Kent

This paper introduces a reporter system to identify and characterize expanded hematopoietic stem cells, showing their molecular profile resembles fetal liver HSCs and shares gene expression signatures with functional HSCs from various sources.

bioRxiv · Jun 18, 2021 · PreprintCell Biology

Defining the transcriptional signature of esophageal-to-skin lineage conversion

M. T. Bejar, P. Jimenez-Gomez, I. Moutsopoulos, B. Colom, S. Han, F. J. Calero-Nieto, B. Göttgens, I. Mohorianu, B. D. Simons, M. Alcolea

This study shows that esophageal epithelial cells can convert to hair follicle identity when exposed to skin stroma, with HIF1a inhibition blocking this transition.

bioRxiv · Feb 19, 2021 · PreprintCell Biology