Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish
M. G. Ferreira, M. El-Maï, M. Marzullo, I. P. de Castro
The paper shows that in telomerase zebrafish mutants, telomere shortening leads to a switch from apoptosis to senescence in tissues, mediated by Akt/Foxo pathway activation.
bioRxiv · Jan 10, 2020 · PreprintCell Biology