cGAS-STING is responsible for aging of telomerase deficient zebrafish
N. Serifoglu, G. Allavena, B. Bastos-Lopes, M. Marzullo, P. Bousounis, E. Trompouki, M. G. Ferreira
This study shows that cGAS-STING contributes to premature aging in telomerase-deficient zebrafish by promoting senescence and inflammation, and its absence rescues aging-related phenotypes.
bioRxiv · Mar 11, 2024 · PreprintCell Biology