The Mechanism of MICU-Dependent Gating of theMitochondrial Ca2+ Uniporter
V. Garg, I. Paranjpe, T. Unsulangi, J. Suzuki, L. S. Milescu, Y. Kirichok
The paper uses patch-clamp analysis to show MICUs do not occlude the mitochondrial Ca2+ uniporter but enhance its activity with elevated cytosolic Ca2+.
bioRxiv · Apr 4, 2020Biophysics