Author

I. Ragoussis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Approach:deep learning· 3 Research Focus:differential expression· 3 Research Focus:clustering· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

G. Bourque· 2 shared A. de Weck· 1 shared A. Ozkan· 1 shared A. Russell· 1 shared B. Schilling· 1 shared C. Goubert· 1 shared C. Higgins· 1 shared C. M. Schürch· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBioinformatics

G. Bourque

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Author profile →

4 papers

Recent·Most cited

Integrated genotyping, annotation and epigenetic characterization of transposable elements with GraffiTE

C. Goubert, R. Laflamme, R. Eveleigh, I. Ragoussis, T. Wheeler, G. Lettre, G. Bourque, Cristian Groza

GraffiTE v1.1 is a Nextflow pipeline that genotypes structural variants, annotates polymorphic mobile elements, and maps epigenetic data to transposable elements using pangenome graphs, revealing hypomethylated elements and age-related demethylation.

bioRxiv · Nov 9, 2026 · PreprintBioinformatics

Concerted epithelial and stromal changes during progression of Barrett's Esophagus to invasive adenocarcinoma exposed by multi-scale, multi-omics analysis

M. Strasser, D. L. Gibbs, P. Gascard, J. Bons, J. W. Hickey, C. M. Schürch, Y. Tan, S. Black, P. Chu, A. Ozkan, N. Basisty, V. Sangwan, J. Rose, S. Shah, S. Camilleri-Broet, , L. L. Ferri

This study uses multi-omics analysis to show coordinated changes in epithelial, stromal, and immune compartments during Barrett's Esophagus progression to adenocarcinoma, revealing early appearance of cancer-associated fibroblasts and immunosuppressive microenvironment.

bioRxiv · Jun 8, 2023 · PreprintCancer Biology

Single-cell analysis of childhood leukemia reveals a link between developmental states and ribosomal protein expression as a source of intra-individual heterogeneity

M. Caron, P. St-Onge, T. Sontag, Y. C. Wang, C. Richer, I. Ragoussis, D. Sinnett, G. Bourque

This study analyzes single-cell transcriptomes of childhood leukemia patients to show that developmental state and ribosomal protein expression contribute to intra-individual heterogeneity.

bioRxiv · Jun 27, 2019Cancer Biology

Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific genetic changes associated with immortalisation and malignancy.

R. Veeramachaneni, T. Walker, A. de Weck, T. Revil, D. Badescu, J. O'Sullivan, C. Higgins, L. Elliott, T. Liloglou, J. M. Risk, R. Shaw, L. Hampson, I. Hampson, S. Dearden, R. Woodwards, , N. Thakker

This study identifies stage-specific genetic changes in head and neck squamous cell carcinoma progression, highlighting CSMD1 inactivation as a key factor in early carcinogenesis and metastasis.

bioRxiv · Jul 9, 2018Cancer Biology