Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome
K. J. Forsberg, I. V. Bhatt, D. T. Schmidtke, B. L. Stoddard, B. K. Kaiser, H. S. Malik
The paper identifies potent Cas9 inhibitors from human microbiomes using functional metagenomics, discovering AcrIIA11 as a strong inhibitor with a novel mechanism.
bioRxiv · Mar 6, 2019Microbiology