Redox regulated auto-processing controls delivery of an antibacterial cysteine peptidase toxin
Dinh Quan Nhan, Bonnie J. Cuthbert, Kaitlin A. Schroeder, Christine D. Hardy, Fernando Garza‐Sánchez, Ian H Matthews, Jack R. Kennaday, Michael S. Costello, Celia W. Goulding, Christopher S. Hayes
This study identifies StbD-CT as a redox-regulated cysteine peptidase toxin that auto-processes to activate DNA damage and inhibit bacterial growth.
bioRxiv · May 8, 2026 · PreprintMicrobiology