Author

Christine D. Hardy

University of California, IrvineORCID 0000-0002-0780-025XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Bonnie J. CuthbertiD· 2 shared Celia W. GouldingiD· 2 shared Adrián JinichiD· 1 shared Andy SpenceriD· 1 shared Christopher D. BrowniD· 1 shared Christopher S. HayesiD· 1 shared Dinh Quan NhaniD· 1 shared Dirk SchnappingeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Bonnie J. CuthbertORCID

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Author profile →

2 papers

Recent·Most cited

Redox regulated auto-processing controls delivery of an antibacterial cysteine peptidase toxin

Dinh Quan Nhan, Bonnie J. Cuthbert, Kaitlin A. Schroeder, Christine D. Hardy, Fernando Garza‐Sánchez, Ian H Matthews, Jack R. Kennaday, Michael S. Costello, Celia W. Goulding, Christopher S. Hayes

This study identifies StbD-CT as a redox-regulated cysteine peptidase toxin that auto-processes to activate DNA damage and inhibit bacterial growth.

bioRxiv · May 8, 2026 · PreprintMicrobiology

A periplasmic protein complex supports arabinofuranosyltransferase activity and mediates intrinsic drug resistance in Mycobacterium tuberculosis

Thaís Klevorn, Christopher D. Brown, Christine D. Hardy, Bonnie J. Cuthbert, Andy Spencer, Adrián Jinich, Luming Chan, Shiva K. Angala, Jordan Manzer, Jessica Mendoza, Rodger de Miranda, Heather Kim, Dirk Schnappinger, Mary Jackson, Kyu Young Rhee, , Sabine Ehrt

This study identifies a periplasmic protein complex in Mtb that supports arabinofuranosyltransferase activity and contributes to intrinsic drug resistance.

bioRxiv · Jul 8, 2025 · PreprintMicrobiology