Author

Ian R. Matthews

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

Dylan K. ChaniD· 3 shared Elliott H. SherriD· 3 shared Jiang LiiD· 3 shared Stephanie L. RouseiD· 2 shared Yesai ParkiD· 2 shared Noura Ismail MohamadiD· 1 shared P. K. Santra· 1 shared Yasmin EltawiliD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Dylan K. ChanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Modulating the Unfolded Protein Response with ISRIB Mitigates Cisplatin Ototoxicity

Jiang Li, Stephanie L. Rouse, Ian R. Matthews, Yesai Park, Yasmin Eltawil, Elliott H. Sherr, Dylan K. Chan

This study shows that ISRIB reduces cisplatin-induced hearing loss and hair-cell death without affecting its cytotoxicity in cancer cells.

Scientific Reports · Sep 27, 2024Peer-reviewedNeuroscience

Noise induces intercellular Ca2+ signaling waves and the unfolded protein response in the hearing cochlea

Yesai Park, Jiang Li, Noura Ismail Mohamad, Ian R. Matthews, P. K. Santra, Elliott H. Sherr, Dylan K. Chan

The paper shows that noise exposure causes calcium signaling waves and unfolded protein response in cochlea, with effects dependent on noise intensity.

bioRxiv · Jun 5, 2024 · PreprintNeuroscience

Integrated Stress Response Inhibition Provides Sex-Dependent Protection Against Noise-Induced Cochlear Synaptopathy

Stephanie L. Rouse, Ian R. Matthews, Jiang Li, Elliott H. Sherr, Dylan K. Chan

This study shows ISRIB protects against noise-induced cochlear synaptopathy in male mice but not females, highlighting sex-dependent effects of UPR inhibition.

Scientific Reports · Oct 22, 2020Peer-reviewedNeuroscience