An all-atom view into the disordered interaction interface of the TRIM5α PRYSPRY domain and the HIV capsid
Liam I. Haas-Neill, Deniz Meneksedag‐Erol, Ibraheem Andeejani, Serena del Banco, Jeannette L. Tenthorey, Sarah Rauscher
This paper uses molecular dynamics simulations to analyze the TRIM5α PRYSPRY domain interaction with HIV capsid, revealing structural differences between human and rhesus TRIM5 that explain HIV restriction efficiency.
bioRxiv · Dec 6, 2024 · PreprintBiophysics