Author

Deniz Meneksedag‐Erol

Concordia UniversityORCID 0000-0002-7765-3304Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:statistical model· 3 Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Liam I. Haas-NeilliD· 2 shared Sarah RauscheriD· 2 shared Ayesha Chaudhry· 1 shared Derek J. WilsoniD· 1 shared Elvin D. de AraujoiD· 1 shared Golshad Ghojoghi· 1 shared Huy OngiD· 1 shared Ibraheem Andeejani· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

Liam I. Haas-NeillORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CD36 phosphorylation alters the thrombospondin binding site and reduces internal cavity accessibility and volume

Golshad Ghojoghi, Sylvain Chemtob, William D. Lubell, Huy Ong, Deniz Meneksedag‐Erol

This study uses computational methods to analyze how CD36 phosphorylation alters its structure, affecting TSP-1 binding and fatty acid uptake.

bioRxiv · Sep 1, 2026 · PreprintBiophysics

Molecular Modulation of the SAM-I Riboswitch Drives Global Dynamical Shifts

Vrinda Nair, Mohammadreza Niknam Hamidabad, Deniz Meneksedag‐Erol, Rachael A. Mansbach

The paper studies how different ligands interact with the SAM-I riboswitch, revealing conformational changes and insights for RNA-targeting drug design.

bioRxiv · Mar 27, 2026 · PreprintMolecular Biology

The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain

Liam I. Haas-Neill, Deniz Meneksedag‐Erol, Ayesha Chaudhry, Masha Novoselova, Qirat F. Ashraf, Elvin D. de Araujo, Derek J. Wilson, Sarah Rauscher

This study investigates how the N642H mutation in STAT5B stabilizes the parallel dimer through changes in hydrogen bonding, using molecular dynamics simulations and HDX mass spectrometry.

Protein Science · Dec 26, 2024Peer-reviewedBiophysics

An all-atom view into the disordered interaction interface of the TRIM5α PRYSPRY domain and the HIV capsid

Liam I. Haas-Neill, Deniz Meneksedag‐Erol, Ibraheem Andeejani, Serena del Banco, Jeannette L. Tenthorey, Sarah Rauscher

This paper uses molecular dynamics simulations to analyze the TRIM5α PRYSPRY domain interaction with HIV capsid, revealing structural differences between human and rhesus TRIM5 that explain HIV restriction efficiency.

bioRxiv · Dec 6, 2024 · PreprintBiophysics