Author

Serena del Banco

Fred Hutch Cancer CenterORCID 0000-0002-3466-1865Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Jeannette L. TenthoreyiD· 2 shared Chang LiuiD· 1 shared Deniz Meneksedag‐EroliD· 1 shared Harmit Singh MalikiD· 1 shared Hayley Klingenberg· 1 shared Ibraheem Andeejani· 1 shared Ishrak Ramzan· 1 shared Liam I. Haas-NeilliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersEvolutionary Biology

Jeannette L. TenthoreyORCID

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2 papers

Recent·Most cited

Evolutionary BiologyCell GenomicsPeer-reviewedMar 26, 2025

Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations

Jeannette L. Tenthorey, Serena del Banco, Ishrak Ramzan…·Harmit Singh Malik

The paper shows that indels, not just missense mutations, enable antiviral proteins like TRIM5 to evolve new functions against viruses.

9 citations

humanproteomics

BiophysicsbioRxivPreprintDec 6, 2024

An all-atom view into the disordered interaction interface of the TRIM5α PRYSPRY domain and the HIV capsid

Liam I. Haas-Neill, Deniz Meneksedag‐Erol, Ibraheem Andeejani…·Sarah Rauscher

This paper uses molecular dynamics simulations to analyze the TRIM5α PRYSPRY domain interaction with HIV capsid, revealing structural differences between human and rhesus TRIM5 that explain HIV restriction efficiency.

1 citation

humanstructural biology