Live Cell Partial Wave Spectroscopic microscopy: Label-free Imaging of the Native, Living Cellular Nanoarchitecture
Luay M Almassalha, Greta Bauer, John Chandler, Scott Gladstein, Lusik Cherkezyan, Yolanda Stypula-Cyrus, Sam Weinberg, Di Zhang, Peder Thusgaard Ruhoff, Hemant Roy, Hariharan Subramanian, Navdeep Chandel, Igal Szleifer, Vadim Backman
This paper develops live cell Partial Wave Spectroscopic (PWS) microscopy to study chromatin nano-architecture dynamics in real-time, showing changes in chromatin structure due to DNA damage and linking it to mitochondrial membrane potential.
bioRxiv · Jul 2, 2016Bioengineering