BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Molecular mechanism of substrate transport by human peroxisomal ABCD3
Meghna Gupta, Nitesh Khandelwal, Devin J. Seka…·Robert Michael Stroud
This study determines the cryo-EM structures of human ABCD3 in apo and substrate-bound states, revealing how substrate binding induces ATPase activity and provides structural insights into its transport mechanism.