Cerebral organoid proteomics reveals signatures of dysregulated cortical development associated with human trisomy 21
Tristan D. McClure‐Begley, Christopher C. Ebmeier, Kerri A. Ball, Jeremy R. Jacobsen, Igor Kogut, Ganna Bilousova, Michael W. Klymkowsky, William M. Old
This study uses cerebral organoid proteomics to identify dysregulated networks in trisomy 21 and shows harmine partially normalizes key developmental regulators.
bioRxiv · May 5, 2018 · PreprintSystems Biology