Kerri A. Ball

Mitochondrial Signaling: Nitric Oxide Synthesis by Cytochrome c Oxidase and Its Oxygen Sensitivity Are Modulated by Adenine Nucleotides

The paper examines how adenine nucleotides modulate nitric oxide synthesis by cytochrome c oxidase in mitochondria, showing differential effects of ADP and ATP and isoform-specific responses under hypoxia.

The APE2 nuclease is essential for DNA double strand break repairby microhomology-mediated end-joining.

This study identifies APE2 nuclease as a critical factor for MMEJ repair, showing its role in telomere fusion and DNA repair reporter assays.

Multi-Omic Analysis Reveals Cannabidiol Disruption of Cholesterol Homeostasis in Human Cell Lines

This study shows CBD disrupts cholesterol homeostasis in human cell lines, altering metabolites, transcripts, and proteins related to cholesterol biosynthesis, transport, and storage.

Cerebral organoid proteomics reveals signatures of dysregulated cortical development associated with human trisomy 21

This study uses cerebral organoid proteomics to identify dysregulated networks in trisomy 21 and shows harmine partially normalizes key developmental regulators.

Unexpected Early Proteomic Changes in Alzheimer’s Disease Model Mice Synaptosomes

The paper uses proteomics to identify early changes in AD model mice synaptosomes, finding significant proteomic alterations before traditional disease markers appear.