A humanized yeast phenomic model of deoxycytidine kinase to predict genetic buffering of nucleoside analog cytotoxicity
Sean M. Santos, Mert Icyuz, Ilya Pound, Doreen William, Jingyu Guo, Brett Allen McKinney, Michael Niederweis, John W. Rodgers, John L. Hartman
The paper uses a humanized yeast model to predict genetic buffering of nucleoside analog cytotoxicity by analyzing drug-gene interactions in cancer cell lines.
Genes · Sep 30, 2019Peer-reviewedSystems Biology