Author

Sean M. Santos

University of Alabama at BirminghamORCID 0000-0003-2166-8395Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Systems Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:yeast· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

John L. HartmaniD· 3 shared John W. RodgersiD· 2 shared Audrie Broadway· 1 shared Brett Allen McKinneyiD· 1 shared Cosby Burnet· 1 shared Daniel L. SmithiD· 1 shared Doreen WilliamiD· 1 shared Ilya Pound· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersSystems Biology

John L. HartmanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GeneticsGeroSciencePeer-reviewedOct 4, 2020

High-resolution yeast quiescence profiling in human-like media reveals interacting influences of auxotrophy and nutrient availability

Sean M. Santos, Samantha Laflin, Audrie Broadway…·John L. Hartman

The paper investigates factors influencing yeast quiescence using defined media, revealing interactions between auxotrophy, nutrient availability, and signaling pathways.

10 citations

yeastexperimental assay

𝕏 PostBluesky

Systems BiologyCancer & MetabolismPeer-reviewedOct 23, 2019

A yeast phenomic model for the influence of Warburg metabolism on genetic buffering of doxorubicin

Sean M. Santos, John L. Hartman

The paper uses yeast phenomics to model how Warburg metabolism affects genetic buffering of doxorubicin, identifying key biological processes and predicting causal gene expression effects on anti-cancer efficacy.

8 citations

yeaststatistical model

𝕏 PostBluesky

Systems BiologyGenesPeer-reviewedSep 30, 2019

A humanized yeast phenomic model of deoxycytidine kinase to predict genetic buffering of nucleoside analog cytotoxicity

Sean M. Santos, Mert Icyuz, Ilya Pound…·John L. Hartman

The paper uses a humanized yeast model to predict genetic buffering of nucleoside analog cytotoxicity by analyzing drug-gene interactions in cancer cell lines.

5 citations

yeaststatistical model

𝕏 PostBluesky