Bile Acid Scaffold Engineering Reveals an Androstane-Triol Derivative as a Potent Immunomodulator with Therapeutic Efficacy in EAE
Laura Calvo‐Barreiro, Imane Boutitah-Benyaich, Herena Eixarch, Carmen Espejo, Moustafa Tarek Gabr
This paper identifies BA59, an androstane-triol derivative, as a potent immunomodulator that reduces disease severity in experimental autoimmune encephalomyelitis by modulating T cell balance and antigen-presenting cell function.
Journal of Neuroinflammation · Mar 12, 2026Peer-reviewedPharmacology & Toxicology