Pharmacology & ToxicologyJournal of NeuroinflammationPeer-reviewed
Bile Acid Scaffold Engineering Reveals an Androstane-Triol Derivative as a Potent Immunomodulator with Therapeutic Efficacy in EAE
Laura Calvo‐Barreiro, Imane Boutitah-Benyaich, Herena Eixarch…·Moustafa Tarek Gabr
This paper identifies BA59, an androstane-triol derivative, as a potent immunomodulator that reduces disease severity in experimental autoimmune encephalomyelitis by modulating T cell balance and antigen-presenting cell function.
DOI 10.1186/s12974-026-03768-5