Genomic Specificity of Anti-TCR mAbs determined by single-cell RNAseq
Ian Magill, Val Piekarsa, Σοφία Κοσσίδα, Joshua D. Croteau, Amy Huei‐Yi Lee, ROBERT S. BALDERAS, David Zemmour, Christophe O. Benoist, immgenT Project, Aaron C. Liu, Alexander V. Chervonsky, Alexandra Cassano, Alia Welsh, Ananda W. Goldrath, Andrea Lebron Figueroa, , Xutong Gong
The paper identifies TCR-V gene usage patterns in T cells sorted by anti-TCR mAbs using single-cell RNAseq and finds enriched ERV1-family LTR expression in specific TRBV regions.
The Journal of Immunology · Aug 1, 2025Peer-reviewedImmunology