Minimal detection and low biological fluctuation of mitochondrial CpG methylation at the single-molecule level
Chloé Goldsmith, Jesús Rafael Rodríguez‐Aguilera, Ines El-Rifai, Adrien Jarretier-Yuste, Valérie Hervieu, Victoria Chagoya de Sánchez, Robert Dante, Gabriel Ichim, Héctor Hernández‐Vargas
This study develops a tool to detect mtDNA CpG methylation using long-read sequencing and finds low, stable levels across biological processes with limited variation.
bioRxiv · Sep 14, 2020 · PreprintGenomics