Early resident NK cell response to local HIV infection in lymphoid tissue
David Perea, Alba Gonzalez, Nerea Sánchez-Gaona, Félix Pumarola, Nuria Ortiz, Ines Llano, Juan Lorente, Vicenç Falcó, Meritxell Genescà, Maria José Buzón
This study identifies a distinct cytotoxic NK cell subset in human tonsils that targets HIV-infected CD4 T cells, revealing functional alterations and reprogramming in response to HIV infection.
bioRxiv · Feb 17, 2025 · PreprintImmunology