Meritxell Genescà

The paper identifies tissue-specific entry factors for SARS-CoV-2 in human tissues using single-cell analysis and functional validation.

The paper identifies inducible HIV reservoirs in tonsillar, intestinal, and cervical tissues using tissue models, revealing tissue-specific markers and the effectiveness of different latency reversal agents.

This study evaluates the effect of combining antiretroviral therapy (ART) with TIGIT or KLRG1 blockade in humanized mice, showing improved HIV-1 suppression and delayed viral rebound.

Combining dendritic cell stimulation with anti-TIGIT antibodies enhances memory NK cell cytotoxicity against HIV-1 infected CD4+ T cells in vitro and in vivo.

This study shows that sequential IL-15 and TGF-β1 stimulation expands HIV-specific CD8+T cells with enhanced effector functions, improving HIV control during treatment interruption.

This study identifies a distinct cytotoxic NK cell subset in human tonsils that targets HIV-infected CD4 T cells, revealing functional alterations and reprogramming in response to HIV infection.