Modelling the within-host spread of SARS-CoV-2 infection, and the subsequent immune response, using a hybrid, multiscale, individual-based model. Part I: Macrophages.
Christopher Rowlatt, Mark A. J. Chaplain, David J. Hughes, Stephen H. Gillespie, David Harold Dockrell, Ingólfur Johannessen, Ruth Bowness
This paper develops a hybrid, multiscale, individual-based model to study SARS-CoV-2 infection spread and immune response, focusing on macrophages and their interactions with viral dynamics and cytokines.
bioRxiv · May 6, 2022 · PreprintSystems Biology