Differential LRRK2 signalling and gene expression in WT-LRRK2 and G2019S-LRRK2 mouse microglia treated with zymosan and MLi2.
Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceição Bettencourt, Alice Kaganovich, Thomas T. Warner, John Hardy, Patrick Alfryn Lewis, Jennifer M. Pocock, Mark Cookson, Rina Bandopadhyay
The paper examines gene expression changes in microglia from LRRK2-WT and G2019S knock-in mice treated with zymosan and MLi-2, identifying differential expression patterns and potential PD-related pathways.
Cells · Dec 26, 2023Peer-reviewedNeuroscience