Rina Bandopadhyay

This study quantifies PAK6 and 14-3-3 gamma in plasma to assess their potential as biomarkers for diagnosing sporadic and LRRK2-linked Parkinson's disease.

The paper examines gene expression changes in microglia from LRRK2-WT and G2019S knock-in mice treated with zymosan and MLi-2, identifying differential expression patterns and potential PD-related pathways.

This study shows that the LRRK2 G2019S mutation impairs EAAT2 trafficking, leading to reduced glutamate clearance and potential neurodegeneration in Parkinson's disease.

The paper examines post-translational modifications of alpha-synuclein in Parkinson's disease and Multiple System Atrophy using immunohistochemistry to identify predominant PTMs in pathological aggregates.

This study shows that LRRK2 G2019S kinase activity promotes NSF aggregation, which is toxic to neurons, and that autophagy can clear these aggregates and improve motor and cognitive function in a mouse model.