Author

Irene Amalaraj

Indiana University Indianapolis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andre De Oliveira· 1 shared Arianna Harris-KawanoiD· 1 shared Emily Kristen SimsiD· 1 shared Ernesto Satoshi NakayasuiD· 1 shared Ivo Díaz LudovicoiD· 1 shared Jacob R. EnriqueziD· 1 shared Javier E. FloresiD· 1 shared Josie EderiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Andre De Oliveira

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1 paper

Recent·Most cited

Proinflammatory stress activates neutral sphingomyelinase 2 based generation of a ceramide-enriched β cell EV subpopulation

Zhiwei Xu, Irene Amalaraj, Andre De Oliveira, Arianna Harris-Kawano, Jacob R. Enriquez, Raghavendra G. Mirmira, Josie Eder, Meagan Burnet, Ivo Díaz Ludovico, Javier E. Flores, Ernesto Satoshi Nakayasu, Emily Kristen Sims

This study shows that proinflammatory stress in beta cells increases ceramide-enriched extracellular vesicles via nSMase2, which may affect paracrine signaling in diabetes.

Diabetes · Sep 2, 2025Peer-reviewedMolecular Biology