Author

Irene Broughan

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Amarnath NatarajaniD· 1 shared Fangfang QiaoiD· 1 shared Gary E. SchiltziD· 1 shared Karl A. ScheidtiD· 1 shared Raymond C. BerganiD· 1 shared T.A. Binkowski· 1 shared Wayne F. AndersoniD· 1 shared Weining CheniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Amarnath NatarajanORCID

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1 paper

Recent·Most cited

Protein Structure Inspired Drug Discovery

Fangfang Qiao, T.A. Binkowski, Irene Broughan, Weining Chen, Amarnath Natarajan, Gary E. Schiltz, Karl A. Scheidt, Wayne F. Anderson, Raymond C. Bergan

The paper uses protein 3D structure analysis to discover novel anticancer compounds by targeting unique structural motifs, identifying Dxr2-017 as a selective inhibitor of melanoma cells.

Cancers · Sep 17, 2024Peer-reviewedCancer Biology