Polo-like kinase Cdc5 orchestrates Cdk1 regulation via Swe1 and Mih1 during meiotic prophase I exit
Sara González-Arranz, Isabel Acosta, Irene Gil-Torres, Ethel Queralt, Beatriz Santos, Pedro A. San-Segundo
The paper shows Cdc5 promotes Cdk1 activation during meiotic prophase I exit by inducing Swe1 degradation and facilitating Mih1 nuclear translocation, revealing a novel role for Cdc5 in meiotic progression.
Communications Biology · Apr 2, 2026Peer-reviewedCell Biology