Downregulation of Gankyrin/PSMD10 affects cancer cell growth and proliferation in glioblastoma: in vitro and in vivo study
Daria Yu. Travnikova, Vera S. Shashkovskaya, Maria Kordyukova, Irina Nosova, Olga M. Kudryashova, Timofei S. Zatsepin, Vsevolod Vadimovich Belousov, Tatiana O. Abakumova
This study shows that downregulating Gankyrin/PSMD10 in glioblastoma cells reduces proliferation, increases apoptosis, and enhances chemotherapy effectiveness in vitro and in vivo.
bioRxiv · Dec 2, 2024 · PreprintCancer Biology