The oncogene SLC35F2 is a high-specificity transporter for the micronutrients queuine and queuosine
Lyubomyr Burtnyak, Yifeng Yuan, Erwina Stojek, Xiaobei Pan, Lankani Gunaratne, Gabriel Silveira d’Almeida, Claire Fergus, Maria Martinelli, Colbie Reed, Jessie Fernandez, Bhargesh Indravadan Patel, Isaac Marquez, Ann E. Ehrenhofer‐Murray, Manal A. Swairjo, Juan D. Alfonzo, , Valérie de Crécy‐Lagard
This paper identifies SLC35F2 as a high-specificity transporter for queuine and queuosine in multiple species and shows its role in regulating intracellular levels of these micronutrients.
Proceedings of the National Academy of Sciences · Jun 17, 2025Peer-reviewedBiochemistry