Localized control of protein phase separation via membrane binding
Isabel LuValle-Burke, Giacomo Bartolucci, Daxiao Sun, Xueping Zhao, Christoph A. Weber, Alf Honigmann
This study investigates how membrane binding influences 2D versus 3D phase separation of the protein FUS, showing that membrane binding allows 2D condensates to form at lower concentrations than bulk phase separation.
bioRxiv · Nov 14, 2025 · PreprintBiophysics