Bile Acids Regulate Accumbal Cholinergic Circuitry and Dopamine Release through TGR5 Activation
Isabella A Roque, Shimran S Sharma, Philipp Mews, Summer L. Thompson, Jordan T. Yorgason
This study shows bile acids modulate cholinergic interneuron activity and dopamine release in the nucleus accumbens via TGR5 activation and concentration-dependent effects.
bioRxiv · Mar 2, 2026 · PreprintNeuroscience